Marijuana Use by Older Adults

As of May 2016, twenty-four states have enacted laws to legalize medical marijuana, and four states have legalized marijuana for recreational use(1).  In a recent Gallup poll, 58% of surveyed American adults indicated that marijuana use should be legal, more than double the percentage who did so (25%) in 1995 (2).  As acceptance of cannabis use is on the increase across the country, it is important to consider the implications for the fastest growing segment of the population, older adults(3).

How Many Older Adults Use Marijuana?

Research indicates that cannabis use by older adults is on the rise.  According to data from the annual National Survey of Drug Use and Health (NSDUH), from 2002-2014 the proportion of adults aged 50 to 64 who reported cannabis use in the past year more than tripled from 2.9% to 9.0%.  Among adults aged 65 or older, the proportion increased more than tenfold from 0.2% to 2.1%.  As the baby boom generation has only recently begun to reach senior citizen status and as medical and recreational marijuana use is increasingly decriminalized across the country, the proportion of older adults using cannabis could continue to grow and approach rates currently observed in younger age groups, which as of the NSDUH of 2014, were 11.6% of those aged 35 to 49, 20.0% of those aged 26-34, and 31.9% of those aged 18-25.

Older adult marijuana use

In Washington State

Among older adults, marijuana use in the past 30 days has increased over the last several years, and this increase is higher in Washington State than in the US overall.  From 2011 to 2014, the proportion of older adults aged 50-64 who have used marijuana in the past 30 days grew from 4.4% to 6.1%.  In Washington State, that proportion grew from 6.0% to 8.7%.  Among those aged 65 or older, the proportion having recently used marijuana grew from 0.9% to 1.3% in the US overall and from 0.9% to 2.4% in Washington State.  The Washington Poison Center reports calls about marijuana by age group; although most marijuana-related calls are from younger people, the number of calls from older adults increased from 2014 to 2015.


Source: Behavioral Risk Factors Surveillance System

Source: Washington Poison Control Center 2015 Annual Cannabis Report


What Are Some Concerns About Older Adults and Cannabis Use?

Along with aging come physical changes, including hearing impairment, vision changes, slowed reaction time, susceptibility to falls, and cognitive decline.  Aging also entails the development of age-related health problems, such as cardiovascular disease, diabetes, arthritis, osteoporosis, and cancer.  Two out of three older Americans have multiple chronic health conditions, which generally require multiple prescription medications, increasing the risk of adverse drug effects, which can further endanger their health(4).   As cannabis is increasingly seen as benign and a safe adjunct or alternative treatment for age-related health problems, a rising number of older adults may be expected to turn to marijuana for medical in addition to recreational purposes.

Concerns about Health Harms

Cannabis consumption has a number of acute physiological effects that may be more hazardous or concerning for older adults. 

Concerns about Drug Interactions

According to the Mayo Clinic, cannabis may interact, sometimes dangerously so, with several medications that are commonly prescribed to older adults(8).   Cannabis affects the liver’s cytochrome P450 enzyme system (CYP450), which determines how certain drugs, herbs, and supplements are metabolized.   Those who take medications, herbs, or supplements that are metabolized by CYP450 could have increased blood levels of their active ingredients, which could cause increased effects or potentially serious adverse reactions.   Some specific concerns are listed below.

Concerns about Memory Problems

Age-associated cognitive decline is common in older adults.  Research suggests that more than 10% of older adults aged 60-64 show some age-associated cognitive decline, and the proportion of individuals with cognitive decline increases with age(9).  This is important to consider because cannabis often has cognitive effects, and it is largely unknown how cannabis-related cognitive effects interact with age-related cognitive decline.  Studies on the cognitive effects of cannabis, conducted with younger adults, indicate that the primary psychoactive ingredient in cannabis, delta-9-tetrahydrocannabinol (THC), impairs attention, executive cognitive function, and short-term memory(10, 11).  Such effects could be magnified among older adults who consume cannabis and become problematic, for example, if they interfere with optimal adherence to medication regimens, increase the risk of accidents in the home, or affect decision-making around driving under the influence of cannabis, which could be more hazardous among older adults with subtle or obvious cognitive decline.  Research has found, in young adults, residual cognitive effects of cannabis persist for 12 to 24 hours after smoking.  Residual effects have not been studied in older adults, but it might be expected that residual effects would even last longer in those with age-related cognitive decline.

Concerns about Cannabis Misuse

Generally speaking, older adults are less likely to exhibit substance use disorders than younger adults(12).  However, as cannabis use becomes more widespread among older adults, cannabis misuse, abuse, or dependence would also be expected to rise.  One study indicated that the number of adults aged 50 or older with substance use disorder is projected to double from an average of 2.8 million per year 2002–2006 to 5.7 million in the year 2020(13).  Research published in the Journal of the American Medical Association showed that rates of cannabis abuse and dependence increased modestly but significantly among those aged 45 to 64 from 1991-1992 to 2001-2002 (14) and again from 2001-2002 to 2012-2013(15).

While there is no research to suggest whether older adults are any more or less susceptible to the development of substance use disorders than younger adults, aging is associated with a number of psychosocial problems that serve as risk factors for substance misuse, including bereavement, social isolation, loneliness, lack of social support, depression, and anxiety.  Although most older adults have regular contact with health professionals for a variety of reasons, relatively few with substance use problems seek professional help(16).   This may be particularly true for cannabis, given the widespread belief that cannabis is not addictive(17).  While treatments designed specifically for older adults are few and have rarely been tested, response to treatment for substance use disorders appears to be at least as good among older adults as among younger adults(18)

Conclusion

In summary, there are a number of concerns about cannabis use among older adults.  Older adults who use cannabis, especially those who are concerned about their use of cannabis, might start by talking with their primary care providers about this issue.  Primary care providers are in the best position to advise older adults about their use of cannabis in the context of each individual’s current health status.  Primary care providers should also be able to provide referrals to those seeking treatment to reduce or discontinue their use of cannabis.  Washington State residents can call the Recovery Helpline at (866) 789-1511.  Individuals from any state can call Marijuana Anonymous at (800) 766-6779.  A free online program to reduce or discontinue cannabis use is also available at Reduce Your Use. For other resources, see Where to Get Help.

References

  1. State Marijuana Laws Map. Governing. View website (last retrieved May 2016)
  2. Jones JM. In U.S., 58% Back Legal Marijuana Use. Gallup Organization, Oct. 15, 2015. Free online
  3. U.S. Census Bureau, Nov. 30, 2011.
  4. Centers for Disease Control & Prevention. The State of Aging & Health in America, 2013. Free online
  5. Wu TC, Tashkin DP, Djahed B, Rose JE. Pulmonary hazards of smoking marijuana as compared with tobacco. New England Journal of Medicine 1988;318(6):347-51. View abstract
  6. Tashkin DP, Baldwin GC, Sarafian T et al. Respiratory and immunologic consequences of marijuana smoking. Journal of Clinical Pharmacology 2002;42(S1):71S-81S. View abstract
  7. Sidney S.  Cardiovascular consequences of marijuana use. Journal of Clinical Pharmacology 2002;42(S1):64S-70S. View abstract
  8. Mayo Clinic. Drugs and Supplements: Marijuana (Cannabis sativa). View website (last retrieved May 2016).
  9. Schönknecht P, Pantel J, Kruse A, Schröder J. Prevalence and natural course of aging-associated cognitive decline in a population-based sample of young-old subjects. American Journal of Psychiatry 2005; 162(11):2071-7 View abstract
  10. Ranganathan M, D’souza DC. The acute effects of cannabinoids on memory in humans: a review. Psychopharmacology 2006;188(4):425-44. View abstract
  11. Lundqvist T. Cognitive consequences of cannabis use: comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions. Pharmacology Biochemistry and Behavior 2005;81(2):319-30. View abstract
  12. Gum AM, King-Kallimanis B, Kohn R. Prevalence of mood, anxiety, and substance-abuse disorders for older Americans in the national comorbidity survey-replication. American Journal of Geriatric Psychiatry 2009;17(9):769-81. View abstract
  13. Han B, Gfroerer JC, Colliver JD, Penne MA. Substance use disorder among older adults in the United States in 2020. Addiction 2009;104(1):88-96. View abstract
  14. Compton WM, Grant BF, Colliver JD et al. Prevalence of marijuana use disorders in the United States: 1991-1992 and 2001-2002. JAMA 2004;291(17):2114-21. View abstract
  15. Hasin DS, Saha TD, Kerridge BT et al. Prevalence of marijuana use disorders in the United States Between 2001-2002 and 2012-2013. JAMA Psychiatry 2015;72(12):1235-42. View abstract
  16. Gossop M, Moos R. Substance misuse among older adults: a neglected but treatable problem. Addiction 2008;103(3):347-8. View abstract
  17. Roffman R, Stephens RS. Cannabis Dependence: Its Nature, Consequences and Treatment. Cambridge University Press, 2006. (International Research Monographs in the Addictions)
  18. Satre DD. Alcohol and drug use problems among older adults. Clinical Psychology: Science and Practice 2015;22(3):238-54. View abstract

Citation: Stoner SA. Marijuana Use by Older Adults.  Alcohol & Drug Abuse Institute, University of Washington, May 2016.  URL: http://LearnAboutMarijuanaWA.org/factsheets/olderadults.htm.

This report was produced with support from the I-502 Marijuana Dedicated Fund for research at the University of Washington.